Bone Fragility Study

Bone Fragility: The Material and Micro-architectural Basis and Mechanisms Responsible for Bone Fragility in Spinal Cord Injury in Men

Spinal cord injury leads to profound muscular atrophy, bone loss and bone fragility. This leads to an increased incidence of fractures, which can compromise quality of life, lead to further deterioration in bone quality and compromise rehabilitation. The lifetime risk for fracture in people living with SCI is double the risk relative to a non-injured healthy person.

Criteria for assessing fracture risk in the spinal cord injury population have yet to be defined. High Resolution peripheral quantitative computed tomography (HR-pQCT) provides a potential method for assessing factors other than bone mineral density that contribute to fracture risk. This study will use HR-pQCT in combination with other imaging and assessment techniques to gather comprehensive data related to the pathogenesis and structural basis of bone change after spinal cord injury. The study will recruit people with acute and longstanding SCI as well as healthy non-injured volunteers.  It is hoped that the results of this study will provide new insights into possible approaches to preventing and reversing the structural decay in patients with spinal cord injury.

I want to see project details

Our Mission

Spinal Research Institute (SRI) is a not-for-profit spinal cord research charity. Our mission is to support world class clinical research and clinical trials. We provide means for Australian and international spinal cord injury (SCI) researchers to build much needed collaboration and to translate research outcomes into life changing health solutions for people living with SCI.

Support Us

Vital investment is needed to support research into new and better treatments that will improve the quality of life of people living with spinal cord injury... Be part of it!

Tweet Feed

Be our Partner

Here at The SRI we encourage businesses and organisations of all sizes to recognise the importance of Corporate Social Responsibility and to strive to be great corporate citizens by aligning our brands for bigger and better outcomes. With us you can make an impact – now!